Tumefactive demyelinating disease with isolated spinal cord involvement

نویسندگان

  • Mina S Makary
  • Claudia F Kirsch
چکیده

Tumefactive multiple sclerosis (TMS) is an unusual variant of demyelinating disease. TMS has a variable and unknown progression and presents with features similar to a neoplasm making the determination a diagnostic challenge to clinicians. This report presents one of the very few reported cases of isolated spinal cord TMS, and the second case to describe TMS of the lower spinal cord, given that the lesions are typically cervical. This case study presents a diagnostic approach based on clinical, laboratory, and imaging characteristics, as well as sheds some light on the response to therapy and disease evolution.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Tumefactive demyelination of the spinal cord.

Demyelinating lesions of the brain have been frequently reported to mimic tumors, whereas very few cases of tumefactive demyelination of the spine have been reported. We report a patient with tumefactive demyelination of the spinal cord who was clinically, by MRI, and by frozen section diagnosed with tumor and had complete surgical resection. Hence patients with spinal cord lesions suspicious o...

متن کامل

Tumefactive Multiple Sclerosis in Taiwan

BACKGROUND Multiple sclerosis (MS) is less common in Asia, including Taiwan, and some characteristics of MS in Asians differ from those of Caucasians. Tumefactive brain lesion is even rarer in MS patients. OBJECTIVE To review patients with tumefactive MS and compare them with those in other studies investigating tumefactive demyelinating lesions and our Taiwanese typical MS patients. METHOD...

متن کامل

Tumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis.  Clinical P...

متن کامل

O17: Inflammation in Brain and Spinal Cord

our goal in this paper is to describe and compare basic immunopathologic pattern of common demyelinating disorder, that is very important to choose the best treatment. The most common disorders are multiple sclerosis, neuromyelitis optica,Anti MOG associated disease,ADEM and autoimmune encephalitis. ADEM consists of ‘‘sleeves’’ of demyelination centered on small, engorge...

متن کامل

Isolated lesion of the cervical spine in a case of neuro-Behcet.

Behcet`s disease is characterized by small vessel vasculitis and involvement of multiple systems. In neuro-Behcet cases, spinal cord involvement is approximately 10-18%. Spinal cord lesions are often associated with cerebral or brainstem lesions, and isolated spinal cord involvement in Behcet`s disease is very rare. Here, we report a case with an isolated lesion of the cervical spine.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2014